这意味着这个页面会引导你完成一个特定的任务、战略、或与 敌怪 / Boss 之间的战斗。
- 会在在原处停滞几秒,随后会非常快的向玩家跳跃试图并碾压玩家 , 注意！此时碾压伤害极高(会被秒那种）.
- 会在原处停滞几秒 , 随后会发射六团规则的凝胶，可以在摧毁前反弹两次.在一轮中有几率进行数次这样的攻击.
- Starting the battle just after the sun sets (7:30 PM) will provide the maximum amount of time to defeat nocturnal bosses. In Hardmode, the 月光护身符 and/or 月亮石 are also useful at night.
- Prepare your Boss-fighting arena with adequate lighting, 篝火 and 红心灯笼 for health regeneration, and Stars in Bottles for mana regeneration if you use magic. 韧皮雕像 will provide a significant defensive boost. 花园侏儒 will reduce damage taken and increase damage dealt due to the luck. 蜂蜜 pools can also be used for extra health regeneration.
- 向日葵 provide the Happy! buff to players within a 50-tile radius, which grants a +10% movement speed bonus and 17% reduction in enemy spawn rate.
- Always carry at least one stack of the highest-tier healing potion available (Lesser, 普通,Greater, or 超级治疗药水). Relying only on natural Health Regeneration is not a good idea.
- It is suggested to build houses for the 树妖 and the 护士 NPCs in your arena. The former casts the 树妖祝福 buff, which increases your defense and provides you with a thorns-like effect, while the latter can heal and remove debuffs instantly, at the cost of some 钱币.
- Bosses are displayed on the Minimap: Follow the boss's icon to track it when you're struggling to find it. You can identify the boss icons by checking their respective wiki pages.
- Once you have freed the 机械师 in the Dungeon, you can use 电线 to enhance your arena with 机关 and helpful 心 and 星星雕像. The former help to damage the enemies, though be careful to set them up correctly in order not to hurt yourself during the battle. The latter will spawn heart and star pickups, respectively. Connect these devices to 计时器.
- It may be useful to summon and kill the Eye of Cthulhu or King Slime before summoning any harder boss in order to spawn an extra one-use pool of Hearts. Note that this will prevent any Heart Statues from spawning new Hearts.
- Remember to use the 利器站, 弹药箱, 水晶球,施法桌, and 蛋糕块 before you go to explore or battle bosses/invasions. These will give boosts that are useful to take, with the first four being class-specific. They give 锋利, 弹药箱, 千里眼, 着魔, and Sugar Rush, respectively.
史莱姆皇后会发出难以躲避的反弹弹幕，尤其在第二阶段。在一个底部由平台构成的开阔场地作战就可以让发射的子弹安全地飞出。举个例子，我们就很推荐由平台搭建而成的Sky Bridge 。
- 钛金 或者 精金盔甲 对任何职业类型都是很有帮助的。
- 如果你已经击败了任意一个机械BOSS, 神圣盔甲，由于它的“神圣庇护Holy Protection”的套装效果，神圣套对于任何职业的玩家都是极度有效的 。这使得玩家能够避开史莱姆皇后不少的弹幕，从而无视大量伤害。
- 召唤师和法师可以选择 禁戒盔甲。
- 战士和射手可以选择 寒霜盔甲。
- 飞镖手枪 或 飞镖步枪 ，搭配上 水晶镖 十分实用，因为它们伤害很高，还可以自瞄。这使得你可以杀死所有召唤在你身边的小史莱姆。
- 代达罗斯风暴弓, while also being useful for killing the smaller slimes, can still do a hefty amount of damage to the Queen Slime when paired with Holy/灵液箭 and a 魔法箭袋.
- The 魔晶碎块 dropped by hallowed mimics can deal good damage to Queen Slime and the slimes she summons because of its piercing ability.
- The 水晶蛇 can deal high damage to the Queen Slime because of her large hitbox, but it will not deal with the smaller slimes well.
- The 流星法杖 is a high damage weapon that can be used for most bosses at this point in the game, but it uses a lot of mana very quickly, so a lot of mana potions will be required.
- The 海盗法杖 is the highest damage summon weapon available at this point in the game if no mechanical bosses have been defeated.
- The Sanguine Staff can be used as alternative that requires less grinding to get.
There are many great accessories available at this point.
- The 十字项链 (or any of its upgrades such as the 星星面纱) will make the variety of attacks much more survivable.
- 冰冻之翼, 仙灵之翼, 鸟妖之翼 or 鳍翼 are the best wings available at this stage, but 叶之翼 are reasonable substitutes. 闪电靴 or better will provide better ground movement. Those two accessories will allow you to move almost freely through the air and on the ground.
- The 钴护盾 or its upgrades prevents knockback and it is practically mandatory for melee users, but useful for any class.
- The 冰冻海龟壳 is a defensive accessory that reduces damage if your health starts getting low. The Expert mode exclusive 蠕虫围巾 is also effective.
- The 神话护身符 enhances survivability by providing regeneration and reducing the duration of Potion Sickness. To reduce the potion cooldown, it only needs to be equipped during the instant a health potion is drunk.
- An Emblem provides additional damage for your primary damage type;
- Yoyo fighters should use a 悠悠球袋, as it doubles a yoyo's damage output, as well as providing 2 extra counterweights that can do a bit more damage.
- 魔法箭袋 should be used if using a 代达罗斯风暴弓 or any Repeater with Jester/邪箭.
- Magic users who wish to rely less on Mana Potions can equip a pair of 魔法手铐/天界手铐. Slimes drop mana stars frequently.
- 腐香囊 provides a generic increase to DPS and is a decent filler accessory.
As with most situations in general, it is best to reforge your accessories with damage, critical strike chance or defense increasing modifiers.
- 再生药水, 耐力药水, 生命力药水, and 铁皮药水 will greatly increase survivability.
- Any food item that provides the 吃得好, Plenty Satisfied, or Exquisitely Stuffed buff is helpful.
- 魔力再生药水 is a must for mages.
- 敏捷药水 will increase mobility.
- 暴怒药水 and 怒气药水 will improve DPS.
在第二阶段, 史莱姆皇后的攻击会遵循一个可预测的模式. 玩家可以在一个长平台上来来回回地跑, 同时跳过BOSS发出的弹幕。 与此同时，史莱姆皇后会一直呆在战斗开始时她所在高度附近，这使得瞄准更加容易。
Fighting on a long skybridge can make avoiding the spawned slimes much easier. Queen Slime is fairly slow in her first stage, but her winged form can keep up with the mounts summoned by the Goat Skull and Blessed Apple. Be careful if you reverse directions as all previously summoned slimes will still be alive.