Ichor Bullets are 困難模式 子彈 that inflict the 靈液減益 to 敵怪, decreasing the enemy's defense by 20 points, which effectively can increase the damage from the bullet an additional 10 hit points from its base value of 13, totaling the effective damage of up to 23 (additional 15 hit points in 專家模式, totaling 28 damage). They are the 猩紅 counterpart to the 腐化 詛咒彈s.
- When fighting Bosses, it's advantageous to combine the debuff of the 靈液減益 with other bullets, conserving Ichor Bullets and increasing damage. The player should alternate bullets in their inventory and/or ammo slots; for example, the first slot with 1-10 Ichor Bullets, the second with 100 水晶子彈s, and so on, until there are enough bullets to last the fight. The amount of bullets to place in each slot should be enough for the gun to switch back to Ichor Bullets before the debuff expires (15 seconds).
- 毀滅者, the 拜月教邪教徒 , all 天界塔s , and the 月亮領主 are immune to the Ichor Debuff, making this ammunition mostly useless against them.
- Ichor Bullets reflected by 寶箱怪s in 專家模式 do not inflict the Ichor Debuff on the player.
- 126.96.36.199：Now creates 150 Ichor Bullets per Ichor instead of 50.